Figure 5
From: Axonin-1/TAG-1 is required for pathfinding of granule cell axons in the developing cerebellum
Downregulation of AX-1 does not change the expression of related cell adhesion molecules. We compared expression of related immunoglobulin superfamily cell adhesion molecules between (a,c,e) embryos lacking AX-1 and (b,d,f) age-matched untreated control embryos at HH35, one day after ex ovo RNAi. We found no changes in NgCAM (a,b), NrCAM (c,d), and Contactin/F11 expression (e,f). Inserts in (a,c,e) show adjacent sections stained for EGFP to demonstrate that sections were taken from the electroporated area of the cerebellum. Bar: 100 μm in (a-d), 50 μm in (e,f).