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Figure 3 | Neural Development

Figure 3

From: Forcing neural progenitor cells to cycle is insufficient to alter cell-fate decision and timing of neuronal differentiation in the spinal cord

Figure 3

Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that zone. For each marker, a total of at least 400 transgenic cells were analyzed from 5 independent 40 μm sections from 4 transgenic embryos. Each image represents the maximum projections of 8 optical sections acquired at 5 μm Z steps. (c,d,g,h,k,l,o,p) High magnifications of the zones framed by dashed lines on the adjacent sections.

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