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Table 1 Expression levels of presynaptic and postsynaptic proteins in transforming growth factor-β2 knock-out mice

From: Loss of transforming growth factor-beta 2 leads to impairment of central synapse function

 

Expression level

P-value

Presynaptic proteins

  

   vGat

93 ± 2

NS

   vGlut1

208 ± 101

NS

   vGlut2

80 ± 11

NS

   Synaptotagmin

79 ± 8

NS

   Synaptobrevin

124 ± 16

NS

   Munc13-1

184 ± 40

NS

Postsynaptic proteins

  

   Gephyrin

114 ± 59

NS

   Neuroligin-1*

101 ± 9

NS

   Neuroligin-2

84 ± 23

NS

   Neuroligin-3

90 ± 11

NS

   NMDAR*

152 ± 23

NS

   GlyR*

107 ± 12

NS

  1. Protein levels in postnuclear fraction of brainstem material of embryonic day 18.5 knock-out (KO) embryos, given as percentage of wild-type (WT) levels ± standard error of the mean. WT and KO, n = 4; *WT, n = 4; KO, n = 3. NS, not significant.