Figure 1
From: Loss of transforming growth factor-beta 2 leads to impairment of central synapse function
Phenotype and breathing activity in wild-type (WT) littermates and transforming growth factor (TGF)-β2 knock-out (KO) mice at embryonic day 18.5.(a, b). In comparison to WT embryos (a), TGF-β2 KO mice (b) display a normal gross anatomy, but a hunched posture and no voluntary movement.(c, d) Analysis of breathing activity showed a rhythmic pattern in WT embryos (c) but respiratory failure in KO mice (d). Scale bar, 1 cm (a, b).