Figure 9
From: A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction
Nidogen-2 localized to synaptic sites in the absence of other synaptic basal lamina components. (A-E) Nidogen-2 was properly localized at synaptic sites (labeled with α-bungarotoxin (BTX)) in mutant mice lacking laminin α4 (lama4-/-) (A), laminin α5 (lama5M/M:HSA-Cre) (B), both laminin α4 and α5 (lama4-/-; lama5M/M:HSA-Cre) (C), laminin β2 (lamb2-/-) (D) and all four synaptic collagen IV chains (col4a5-/Y) (E). Scale bar is 5 μm.