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Table 1 The number of second motoneurons is reduced following Met knock down

From: The Met receptor tyrosine kinase prevents zebrafish primary motoneurons from expressing an incorrect neurotransmitter

 

Control

met MO

SB203580

Number of embryos

18

20

16

Percent of segments with ventral nerve

98

61

39

GFP+ somata within 3 cell diameters of floor plate

20 ± 0.47

9 ± 0.61

6 ± 0.40

GFP+ somata 3 cell diameters dorsal of floor plate

5 ± 0.39

10 ± 0.52

8 ± 0.68

  1. GFP-positive SMN axons (three segments/embryo) and somata (two segments/embryo) were analyzed in 48 hpf Tg(gata2:GFP) embryos. Soma counts of treatment groups are all significantly different from controls (p < 0.00015).