Figure 4
From: The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle
Over-expression of skp2 counteracts the effect of skp2 Mo on neural differentiation. (a-e) Embryos were injected with 30 ng skp2 Mo (a), 30 ng Con Mo (d), or 1 ng skp2 (missing first two amino acids) mRNA (b) alone, or together as labelled (c,e), in one blastomere at the two cell stage. ßgal mRNA was co-injected as a lineage tracer. Embryos were analyzed for expression of nßt mRNA at stage 15. Dorsal views with injected side to the right. (f) Percentages of embryos with moderate increase, no change, or moderate or substantial reduction of nßt positive cells on the injected side relative to the uninjected side for each injection.