Figure 11
From: Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers
Correct timing of anchoring center initiation is required for correct folial shape. Superimposition of midline vermis tracings at E17.5, P0, P3 and adult show that the delay in anchoring center formation of the secondary fissure and premature anchoring center formation of the prepyramidal fissure in En2 mutants result in the a misshapen lobule VIII. Grey arrows demarcate prepyramidal fissure; black arrows demarcate secondary fissure.