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Figure 4 | Neural Development

Figure 4

From: Boundary cap cells constrain spinal motor neuron somal migration at motor exit points by a semaphorin-plexin mechanism

Figure 4

Expression of semaphorin genes in the trunk reveals putative repellent ligands are localised to ventral BC cells. (a-f') In situ hybridisations of HH stage 23 chick embryo transverse cryosections (b-f), in parallel with cad7(green) and neurofilament (NF; red) antibody staining on adjacent sections (a,b'-f') show that cad7-positive BC cells at the spinal cord DREZ (red arrows) and MEP (black arrows) express Sema3B (b), Sema3G (e) and Sema6A (f). In contrast, Sema3F (d) is not expressed at the MEP. Prominent expression of Sema3C (c) in motor neurons contrasts with a weak signal in ventral nerve roots. Bar = 100 μm.

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Neural Development

ISSN: 1749-8104