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Figure 2 | Neural Development

Figure 2

From: Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterning

Figure 2

Expression patterns of Sp9 in embryonic mouse forebrain and relationship with the Shh expression domain in ventral telencephalon. (a-i) Comparison of Sp9 and Shh expression. Sp9 expression is not detected in cortex, but it is expressed highly in the SVZ of the MGE, the source of GABAergic interneurons that populate the cortex (arrowheads), and weakly in the LGE that populates interneurons migrating to olfactory bulbs. Sp9 expression domains are observed in the vicinity of the Shh expression domain, but does not overlap them. Ctx, cortex. Scale bars: 0.5 mm.

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