Figure 5From: POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory gangliaBrn3a regulation of Hox gene expression in the DRG. Hox gene expression data were derived from 430A+B array data for E13.5 Brn3a wild-type (wt) and knockout (ko) DRG. Statistically significant increases (p < 0.005) in the knockout were observed for 7 anterior Hox transcripts, and significant decreases were observed (p > 0.995) for two posterior Hox transcripts (asterisks). Similar changes reached statistical significance for 5 anterior Hox genes and one posterior Hox gene in a replicate assay. HoxA7 (parentheses) did not reach statistical significance for detection, indicating high background signal in this probe set. Legend: n.g., no gene at the corresponding position in the cluster; n.d., not determined.Back to article page