Figure 6

Anterograde labeling of retinal terminals in other retino-recipient nuclei. A. Retinal projections in P35 wild-type mice were labeled by intraocular injection of fluorescently conjugated cholera toxin subunit B (CTB). Left eyes were injected with Alexa Fluor 555 CTB (magenta) and right eyes were injected with Alexa Fluor 488 CTB (green). Lateral geniculate nucleus (LGN) from the right hemispheres is shown. ‘Contra’ denotes projections originating from the contralateral retina and ‘ipsi’ denotes projections originating from the ipsilateral retina. Confocal images were acquired from the dorsal lateral geniculate nucleus (dLGN), intergeniculate nucleus (IGL), ventral lateral geniculate nucleus (vLGN), suprachiasmatic nucleus (SCN), olivary pretectal nucleus (OPN), and superior colliculus (SC). IGL is outlined by white dots. B. High magnification images of both contralateral and ipsilateral retinal projections to each region are shown (note - contralateral and ipsilateral panels are not all from the same image). Scale bar in A = 200 μm and in B = 20 μm.